ABS82AF488
MilliporeSigma™ VEGF, Rabbit, Alexa Fluor 488, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS82AF488-Each-of-1 | In Stock | ₹ 38,958.86 |
ABS82AF488 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,958.86
GST (18%): ₹ 7,012.595
Total Price: ₹ 45,971.455
Antigen
VEGF
Classification
Polyclonal
Conjugate
Alexa Fluor 488
Gene
VEGFA, VEGF
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This antibody recognizes VEGF at the N-terminus.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG
Applications
Immunocytochemistry
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody conjugate in PBS with 15mg/ml BSA and 0.1 % Sodium Azide.
Gene Accession No.
P15692
Immunogen
KLH-conjugated linear peptide corresponding to human VEGF at the N-terminus.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_001020537
Target Species
Human
Form
Purified
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Description
- Keratin, type I cytoskeletal 18 (UniProt P05783; also known as Cell proliferation-inducing gene 46 protein, CK-18, Cytokeratin-18, K18, Keratin-18) is encoded by the KRT18 (also known as CYK18, PIG46) gene (Gene ID 3875) in human
- Cytokeratin-18 (Keratin-18 or K18) belongs to a family of highly conserved epithelial-specific intermediate filament (IF) proteins that play an important role in the mechanical stability and integrity of epithelial cells and tissues
- Each epithelium is characterized by its unique keratin expression pattern
- All epithelial cells typically express at least one type-I and one type-II keratin, which form noncovalent heteropolymers
- Keratin 18 is a type I intermediate filament protein that pairs with keratin 8 (K8/K18) in simple epithelia and plays an important role in protecting cells from stress, injury, and apoptosis
- K18 is the only type-I keratin in adult hepatocytes and the major type-I keratin in many colonic tumor cell lines.The structure and function of K8/18 are regulated by posttranslational modifications, such as glycosylation, ubiquitination, and phosphorylation, including K8 phosphorylation on Ser8, Ser23, Ser73, Ser431, and K18 phosphorylation on Ser33 and Ser52
- K18 phosphorylation has been proposed as a progression marker for human chronic hepatitis B (CHB)
- Progressively higher Ser52 phosphorylation is reported in non-cirrhotic and cirrhotic CHB livers, and progressive increase of Ser33 and Ser52 phosphorylation correlates with the elevation of both histological lesions and enzymatic activities of alanine aminotransferase in non-cirrhotic CHB livers.