ABT138225UL
Neurocan, Rabbit anti-Rat, Polyclonal, Millipore Sigma™
Manufacturer: MilliporeSigma
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT138225UL-Each-of-1 | In Stock | ₹ 17,118.26 |
ABT138225UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,118.26
GST (18%): ₹ 3,081.287
Total Price: ₹ 20,199.547
Antigen
Neurocan
Classification
Polyclonal
Formulation
Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Symbols
Ncan;Cspg3
Immunogen
Full-length Neurocan isolated from 7-day embryonic rat brain and purified by monoclonal antibody immunoaffinity chromatography.
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Rat
Isotype
IgG
Applications
Immunofluorescence
Conjugate
Unconjugated
Gene Alias
Neurocan core protein;245 kDa early postnatal core glycoprotein;Chondroitin sulfate proteoglycan 3
Host Species
Rabbit
Molecular Weight of Antigen
135.55 kDa calculated.
Quantity
25 μL
Research Discipline
Cell Structure
Test Specificity
This rabbit polyclonal antibody detects Neurocan in fetal and adult rat brain.
Content And Storage
Stable for 1 year at -20°C from date of receipt.
Related Products
Description
- This rabbit polyclonal Anti-Neurocan, Cat
- No
- ABT1382, is a rabbit polyclonal antibody that detects Neurocan core protein and has been tested for use in Immunofluorescence
- Neurocan core protein (UniProt: P55067; also known as 245 kDa early postnatal core glycoprotein, Chondroitin sulfate proteoglycan 3) is encoded by the Ncan (also known as Cspg3) gene in rat
- Neurocan is a secreted protein of the aggrecan/versican proteoglycan family that is found in early postnatal and adult brain
- During early postnatal development neurocan accounts for at least 20% of the protein of the soluble brain proteoglycans
- Neurocan mostly contains chondroitin sulfate, but also has N-linked and O-linked oligosaccharides
- It is shown to be involved in the modulation of cell adhesion and migration and regulates neurite outgrowth
- Neurocan interact with several cell surface molecules, such as N-CAM, L1/Ng-CAM, etc., and modulates the cell-binding and neurite outgrowth promoting activates of these molecules
- Neurocan is synthesized with a 22 aa signal peptide that is subsequently cleaved to produce the mature form
- Neurocan contains one C-type lectin domain, two EGF-like domains, one Ig-like V type domain, two link domains and one Sushi (CCP/SCR) domain
- (Ref.: Rauch, U., et al
- (2001) Cell Mol
- Life Sci
- 58(12-13):1842-56; Zhou, XH et al
- (2001)
- Mol
- Cell Biol
- 21(17): 5970-78).