AHC1052

CCL5 (RANTES) Monoclonal Antibody (VL1), Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 AHC1052-Each-of-1 In Stock ₹ 44,500.00

AHC1052 - Each of 1

₹ 44,500.00

In Stock

Quantity

1

Base Price: ₹ 44,500.00

GST (18%): ₹ 8,010.00

Total Price: ₹ 52,510.00

Antigen

CCL5 (RANTES)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P13501

Gene Symbols

CCL5

Immunogen

Recombinant human RANTES.

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Applications

ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

VL1

Conjugate

Unconjugated

Gene

CCL5

Gene Alias

beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014)

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

6352

Content And Storage

-20°C

Form

Liquid

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Description

  • CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17
  • Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes
  • The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide
  • CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils
  • It causes the release of histamine from basophils and activates eosinophils
  • This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells
  • It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor
  • Alternative splicing results in multiple transcript variants that encode different isoforms
  • Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.