CCL5 (RANTES) Monoclonal Antibody (947A1H11), Biotin, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AHC6029-Each-of-1 | In Stock | ₹ 40,584.00 |
AHC6029 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,584.00
GST (18%): ₹ 7,305.12
Total Price: ₹ 47,889.12
Antigen
CCL5 (RANTES)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 5mg/mL BSA and 0.5mg/mL sodium azide; pH 7.4
Gene Accession No.
P13501
Gene Symbols
CCL5
Immunogen
Human recombinant RANTES.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA
Clone
947A1H11
Conjugate
Biotin
Gene
CCL5
Gene Alias
beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014)
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6352
Content And Storage
4° C
Form
Liquid
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Description
- Purity is >95% by SDS-PAGE
- This product is recommended as a detection antibody in Sandwich ELISA applications
- CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17
- Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes
- The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide
- CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils
- It causes the release of histamine from basophils and activates eosinophils
- This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells
- It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor
- Alternative splicing results in multiple transcript variants that encode different isoforms
- Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.