APP4698
Phospho-Synapsin 1 (Ser62, Ser67) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APP4698-Each-of-1 | In Stock | ₹ 48,905.50 |
APP4698 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
Phospho-Synapsin 1 (Ser62, Ser67)
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
O88935, P09951, P17600
Gene Symbols
SYN1
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 of rat SYN1 conjugated to KLH
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
SYN1
Gene Alias
Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20964, 24949, 6853
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody is predicted to react with mouse and bovine based on 100% sequence homology
- In Western blot, this antibody is specific for ∽78 kDa synapsin I doublet phosphorylated at Ser 62 and 67
- Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide
- SYN1 (synapsin 1) is a member of the synapsin gene family
- Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles
- Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases
- Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis
- It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal
- Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome
- Alternatively spliced transcript variants encoding different isoforms have been identified.