APPA6715

TACR1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APPA6715-Each-of-1 In Stock ₹ 49,528.50

APPA6715 - Each of 1

₹ 49,528.50

In Stock

Quantity

1

Base Price: ₹ 49,528.50

GST (18%): ₹ 8,915.13

Total Price: ₹ 58,443.63

Antigen

TACR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tacr1

Gene Alias

neurokinin 1 receptor; neurokinin receptor 1; neurokinin receptor subtype NK1; neurokinin-1 receptor; Nk1 receptor; NK-1 receptor; Nk1r; NK-1R; NKIR; SPR; substance p receptor; substance-P receptor; TAC1R; tachykinin receptor 1; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); TACR1; truncated neurokinin-1 receptor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21336, 24807, 6869

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P14600, P25103, P30548

Gene Symbols

Tacr1

Immunogen

A peptide derived from the N-terminus region between amino acids 1-50 of human Neurokinin 1 Receptor. [UniProt# P25103]

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The target sequence has 94% sequence homology with guinea pig
  • Suggested positive control: antigen standard for TACR1 (transient overexpression lysate), SF9 whole cell membrane extracts
  • Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1
  • It is associated with the management of depression, anxiety, and stress
  • It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions
  • The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis
  • Two variants of the tachykinin receptor 1 are produced by alternative splicing
  • Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach
  • ESTs have been isolated from brain and spleen libraries.