Cripto Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APPA6534-Each-of-1 | In Stock | ₹ 49,439.50 |
APPA6534 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
Cripto
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TDGF1
Gene Alias
CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; epidermal growth factor-like cripto protein CR1; Tdgf1; TDGF2; teratocarcinoma-derived growth factor; teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21667, 6997
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P13385, P51865
Gene Symbols
TDGF1
Immunogen
A synthetic peptide made to an N-terminal portion of the murine cripto protein sequence (between residues 1-50).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western blot a band is seen at ∽18 kDa representing the core form of Cripto1, and at ∽36 kDa reporesenting the glycosylated/ post-translationally modified form
- Suggested positive control: MDA-MB231 (human breast cancer) lysates
- Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling
- Cell associated TDGF1 acts as a a Nodeal coreceptor in cis
- Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells
- TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.