APPA6770

LRRK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 APPA6770-Each-of-1 In Stock ₹ 49,350.50

APPA6770 - Each of 1

₹ 49,350.50

In Stock

Quantity

1

Base Price: ₹ 49,350.50

GST (18%): ₹ 8,883.09

Total Price: ₹ 58,233.59

Antigen

LRRK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LRRK2

Gene Alias

4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

120892, 535652, 66725

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.01% sodium azide

Gene Accession No.

Q5S006, Q5S007

Gene Symbols

LRRK2

Immunogen

Synthetic peptide corresponding to the C-terminal residues 2500-2527 of human LRRK2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, C. elegans, Human, Mouse, Plant

Product Type

Antibody

Isotype

IgG

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Description

  • The target sequence has 87% sequence homology with rat
  • LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain
  • Mutations in LRRK2 have been associated with Parkinson's disease
  • LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain
  • The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.