XPC Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APS956-Each-of-1 | In Stock | ₹ 44,455.50 |
APS956 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,455.50
GST (18%): ₹ 8,001.99
Total Price: ₹ 52,457.49
Antigen
XPC
Classification
Polyclonal
Conjugate
Unconjugated
Gene
XPC
Gene Alias
DNA repair protein complementing XP-C cells; DNA repair protein complementing XP-C cells homolog; mutant xeroderma pigmentosum group C; NER; p125; RAD4; Xeroderma pigmentosum group C-complementing protein; Xeroderma pigmentosum group C-complementing protein homolog; xeroderma pigmentosum, complementation group C; XP3; XPC; XPC complex subunit, DNA damage recognition and repair factor; XPCC
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.05% sodium azide
Gene Accession No.
P51612, Q01831
Gene Symbols
XPC
Immunogen
Two synthetic peptides, individually conjugated to the C-Terminus and N-Terminus respectively of human XPC.
Regulatory Status
RUO
Gene ID (Entrez)
22591, 7508
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- PA3-956 detects XPC in human and mouse cells
- PA3-956 has been successfully used in Western blotting and ICC/IF procedures
- By Western blot it detects a ∽125 kDa protein representing XPC
- The PA3-956 immunogen is two synthetic peptides, individually conjugated to the C-Terminus and N-Terminus respectively of human XPC
- This gene encodes a component of the nucleotide excision repair (NER) pathway
- There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc
- This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation
- Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age
- Alternatively spliced transcript variants have been found for this gene.