NBS1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | APSA6528-Each-of-1 | In Stock | ₹ 48,905.50 |
APSA6528 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
NBS1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NBN
Gene Alias
AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Host Species
Rabbit
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Hamster, Human, Mammalia, Mouse, Non-human Primate
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, In Situ Hybridization (ISH), Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with 0.02% sodium azide
Gene Accession No.
O60934, Q9R207
Gene Symbols
NBN
Immunogen
Partial length human NBS1 protein [Swiss-Prot #O60934]
Regulatory Status
RUO
Gene ID (Entrez)
100750782, 27354, 4683
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- ICC/IF has been performed using methanol-fixed IMR90 primary human fibroblasts
- Suggested positive control: antigen standard for NBN (transient overexpression lysate), TK6 and HeLa whole cell extract
- The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex
- This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.