BDB550497

CD91 Mouse anti-Human, PE, Clone: A2MR-A2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB550497-Each-of-1 In Stock ₹ 31,506.00

BDB550497 - Each of 1

₹ 31,506.00

In Stock

Quantity

1

Base Price: ₹ 31,506.00

GST (18%): ₹ 5,671.08

Total Price: ₹ 37,177.08

Antigen

CD91

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

A2MR-A2

Description

Alpha-2-macroglobulin receptor; α2MR; LRP-1; LDL Receptor-Related Protein-1

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Related Products

Img

BD Biosciences

BDB550494

--

Img

BD Biosciences

BDB550805

--

Img

BD Biosciences

BDB555686

--

Img

BD Biosciences

BDB555437

--

Img

BD Biosciences

BDB552884

--

Img

BD Biosciences

BDB555774

--

Img

BD Biosciences

BDB555349

--

Img

BD Biosciences

BDB555345

--

Description

  • Reacts with a 600kDa, type I membrane single protein, also known as the α2 Macroglobulin (α2M) receptor/low density lipoprotein (LDL) receptor
  • The single chain receptor undergoes cleavage, shortly after synthesis, into the 85kDa transmembrane β chain that non-covalently binds to the extracellular 500-515kDa a chain
  • It has a broad cellular distribution, but in the hematopoietic system it is expressed on monocyte lineage cells
  • The α2M/LDL receptor mediates endocytosis of a variety of ligands including α2M-proteinase complexes, plasminogen activators in complex with plasminogen activator inhibitor, Pseudomonas Exotoxin A
  • Ligand binding to α2M/LDL receptor is followed by rapid transport of the ligand to lysosomes for degradation
  • Host Species: Mouse Clone: A2MR-α2 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry