BDB552128
CD180 Rat anti-Mouse, Unlabeled, Clone: RP/14, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552128-Each-of-1 | In Stock | ₹ 32,040.00 |
BDB552128 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,040.00
GST (18%): ₹ 5,767.20
Total Price: ₹ 37,807.20
Antigen
CD180
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Ly78; Ly-78; Lymphocyte antigen 78; RP105; Radioprotective 105 kDa protein
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
RP/14
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
BALB/c mouse splenocytes
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Related Products
Description
- The RP/14 antibody reacts with CD180, the “radioprotective” 105 kDa (RP105) antigen expressed on mature B lymphocytes
- Like other members of the Toll-like Receptor (TLR) family, the extracellular region of CD180 contains tandem repeats of a leucine-rich motif flanked by regions containing conserved cysteines
- These characteristic structural components of TLR may mediate protein-protein interactions and regulation of signal transduction involved in innate immune responses
- Furthermore, CD180 associates with the secretory protein MD-1 on the cell surface
- Cross-linking of cell-surface CD180 with the RP/14 antibody induces activation signals in B lymphocytes
- Despite the expression of CD180 on lymphocytes of all strains tested (BALB/c, BALB/c
- xid , C3H, C57BL/6, CBA/N, and 129/Sv), some strains (BALB/c
- xid , C57BL/6
- xid , CBA/N, 129/Sv, and 129/Ola) display deficient responses to that stimulatory effects of mAb RP/14.