BDB552175

CD197 (CCR7) Rat anti-Human, Unlabeled, Clone: 3D12, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB552175-Each-of-1 In Stock ₹ 17,693.20

BDB552175 - Each of 1

₹ 17,693.20

In Stock

Quantity

1

Base Price: ₹ 17,693.20

GST (18%): ₹ 3,184.776

Total Price: ₹ 20,877.976

Antigen

CD197

Classification

Monoclonal

Concentration

0.5mg/mL

Description

CCR7, BLR-2, EBI-1, CMKBR7

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

3D12

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Human CCR7 protein

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG2a κ

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Description

  • The monoclonal antibody 3D12 reacts with the human CC chemokine receptor, CCR7
  • CCR7 (previously known as BLR-2, EBI-1 and CMKBR7), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CC chemokines, MIP-3β/Exodus 3/ELC/ CCL19 and 6Ckine/Exodus 2/SLC/TCA4/CCL21
  • It has been shown that CCR7 mRNA is expressed mainly in lymphoid tissues including spleen, lymph nodes and tonsil
  • CCR7 mRNA was also detected in peripheral T and B lymphocytes, in bone marrow and cord blood CD34-positive cells and mature dendritic cells
  • The human CCR7 gene, unlike other CC chemokine receptor genes, has been mapped to chromosome 17q12
  • The immunogen used to generate 3D12 hybridoma was the N-terminus as well as parts of the second extracellular loop of human CCR7 protein
  • The monoclonal antibody 3D12 recognizes an epitope mapping to the N-terminus of human CCR7
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.