BDB552532
CD137 Mouse anti-Human, Unlabeled, Clone: H41BB-M127, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB552532-Each-of-1 | In Stock | ₹ 35,066.00 |
BDB552532 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,066.00
GST (18%): ₹ 6,311.88
Total Price: ₹ 41,377.88
Antigen
CD137
Classification
Monoclonal
Concentration
0.5mg/mL
Description
4-1BB, CDw137
Host Species
Mouse
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
ELISA
Clone
H41BB-M127
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- Human 4-1BB, also known as CDw137, is a type I transmembrane glycoprotein belonging to the tumor necrosis factor receptor (TNFR) superfamily
- Naοve T cells lack the 4-1BB, which is not only induced upon T cell activation, but also remains on activated T cells
- It has been reported that the expression of 4-1BB is restricted to primed CD4+ and CD8+ cells
- When triggered by either 4-1BB ligand or antibody ligation, the 4-1BB molecule can act as a co-stimulator to induce T-cell activation and proliferation
- In recent studies, 4-1BB has been emphasized for its effect on the development and survival of functionally active effector CD8 (+) T cells against tumors, virus infections, allogenic immune responses, and for potential therapeutic application.