BDB552559

CD154 Mouse anti-Human, NA/LE, Unlabeled, Clone: HCD40L-M90.1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB552559-Each-of-1 In Stock ₹ 34,888.00

BDB552559 - Each of 1

₹ 34,888.00

In Stock

Quantity

1

Base Price: ₹ 34,888.00

GST (18%): ₹ 6,279.84

Total Price: ₹ 41,167.84

Antigen

CD154

Classification

Monoclonal

Concentration

0.5mg/mL

Description

CD40L

Host Species

Mouse

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

Applications

ELISA

Clone

HCD40L-M90.1

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • Clone hCD40L-M90.1 reacts with CD40 ligand (CD40L), a 39 kDa type II membrane glycoprotein expressed on activated T cells
  • CD40-CD40L interaction plays a very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation
  • In addition, blocking of CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching
  • It has been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that encodes CD40L.