BDB553719
CD152 Hamster anti-Mouse, Unlabeled, Clone: UC10-4F10-11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB553719-Each-of-1 | In Stock | ₹ 29,014.00 |
BDB553719 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,014.00
GST (18%): ₹ 5,222.52
Total Price: ₹ 34,236.52
Antigen
CD152
Classification
Monoclonal
Concentration
0.5mg/mL
Description
CTLA-4
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
UC10-4F10-11
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse CTLA-4 IgG2a Fusion
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG1 κ
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Description
- The UC10-4F10-11 antibody reacts with CD152 (CTLA-4), which is expressed on activated T lymphocytes 2-3 days after stimulation through T cell receptor
- CTLA-4 has significant similarity to CD28 in amino acid sequence, structure, and genomic organization
- Furthermore, CD152 and CD28 share common B7 family counter-receptors
- Unlike CD28, CD152 expression appears to be restricted to activated T cells and CD25+CD4+ regulatory T (Treg) cells
- The stores and the cell surface
- Whereas CD28 delivers a costimulatory signal required for T-cell activation, CTLA-4 is a negative regulator of cell-mediated immune responses
- CD152 may play roles in induction and/or maintenance of immunological tolerance, regulation of protective immunity, and autoimmune responses, and regulation of some aspects of thymocyte maturation
- This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.