BDB554981
CD11b Mouse anti-Rat, Biotin, Clone: WT.5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB554981-Each-of-1 | In Stock | ₹ 36,490.00 |
BDB554981 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,490.00
GST (18%): ₹ 6,568.20
Total Price: ₹ 43,058.20
Antigen
CD11b
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Itgam; Integrin αM chain; Mac-1 α chain; Integrin beta 2 alpha subunit
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
WT.5
Conjugate
Biotin
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Rat neutrophils
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Rat
Isotype
IgA κ
Related Products
Description
- The WT.5 monoclonal antibody specifically binds to CD11b, the α subunit of Mac-1 found on neutrophils and myeloid cells, but not on lymphocytes
- Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface
- Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi
- Neutrophil binding to ICAM-1 is blocked by mAb WT.5
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.