BDB554980

CD11b Mouse anti-Rat, Unlabeled, Clone: WT.5, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554980-Each-of-1 In Stock ₹ 32,574.00

BDB554980 - Each of 1

₹ 32,574.00

In Stock

Quantity

1

Base Price: ₹ 32,574.00

GST (18%): ₹ 5,863.32

Total Price: ₹ 38,437.32

Antigen

CD11b

Classification

Monoclonal

Concentration

0.5mg/mL

Description

Itgam; Integrin αM chain; Mac-1 α chain; Integrin beta 2 alpha subunit

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

WT.5

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Rat neutrophils

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Rat

Isotype

IgA κ

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Description

  • The WT.5 monoclonal antibody specifically binds to CD11b, the α subunit of Mac-1 found on neutrophils and myeloid cells, but not on lymphocytes
  • Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface
  • Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi
  • Neutrophil binding to ICAM-1 is blocked by mAb WT.5
  • This antibody is routinely tested by flow cytometric analysis
  • Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.