BDB554993

CD28 Mouse anti-Rat, NA/LE, Unlabeled, Clone: JJ319, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB554993-Each-of-1 In Stock ₹ 40,406.00

BDB554993 - Each of 1

₹ 40,406.00

In Stock

Quantity

1

Base Price: ₹ 40,406.00

GST (18%): ₹ 7,273.08

Total Price: ₹ 47,679.08

Antigen

CD28

Classification

Monoclonal

Concentration

1.0mg/mL

Formulation

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

Rat CD28-transfected cell line

Quantity

0.5 mg

Research Discipline

Immunology

Target Species

Rat

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

JJ319

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

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Description

  • The JJ319 antibody reacts with CD28, which is expressed on virtually all T lymphocytes bearing αβ T-cell receptors (TCR), on most γδ TCR-bearing T cells, and on a subset of NK cells
  • In the thymus, CD28 expression is developmentally regulated during the maturation of αβ TCR-bearing T cells
  • CD28 is a costimulatory receptor required for activation of T cells; its ligands include CD80 (B7-1) and CD86 (B7-2)
  • Soluble JJ319 mAb costimulates the proliferative responses and IL-2 production of CD4+ and CD8+ T cells activated by anti-αβ-TCR mAb R73 (Cat
  • no
  • 554910)
  • The alternate anti-rat CD28 mAb JJ316 (Cat
  • No
  • 554992) is capable of directly stimulating T cells in vitro and in vivo.