BDB555275

CD3 Molecular Complex Rat anti-Mouse, PE, Clone: 17A2, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555275-Each-of-1 In Stock ₹ 19,046.00

BDB555275 - Each of 1

₹ 19,046.00

In Stock

Quantity

1

Base Price: ₹ 19,046.00

GST (18%): ₹ 3,428.28

Total Price: ₹ 22,474.28

Antigen

CD3 Molecular Complex

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

γδ TCR-positive T-T hybridoma D1

Quantity

0.2 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

17A2

Conjugate

PE

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes
  • Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells
  • The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11
  • This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain
  • In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells.