BDB555280
CD18 Rat anti-Mouse, NA/LE, Unlabeled, Clone: GAME-46, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555280-Each-of-1 | In Stock | ₹ 39,872.00 |
BDB555280 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,872.00
GST (18%): ₹ 7,176.96
Total Price: ₹ 47,048.96
Antigen
CD18
Classification
Monoclonal
Concentration
1.0mg/mL
Description
Integrin β2 chain
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
GAME-46
Conjugate
Unconjugated
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
LFA-1 (CD11a/CD18) from mouse T-cell hybridoma TAM8C41
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG1 κ
Related Products
Description
- The GAME-46 antibody reacts with the common β2 chain of LFA-1 (CD11a/CD18, αLβ2 integrin), Mac-1 (CD11b/CD18, αMβ2 integrin), and gp150, 95 (CD11c/CD18, αXβ2 integrin)
- Expression of CD18 is limited to leukocytes, where it is widely distributed in consort with each of the three integrin α chains (CD11a, CD11b, and CD11c)
- Among splenocytes, NK cells have the highest density of CD18, and T lymphocytes express a higher density than the remaining cells
- The β2 integrins are important mediators of leukocyte-endothelium interactions
- It has been reported that GAME-46 antibody blocks in vitro adhesion of LFA-1-expressing cells to the ligands ICAM-1, ICAM-2 and ICAM-3 and of Mac-1-expressing cells to ICAM-1, C3bi, and fibrinogen.