BDB555303
CD79b Hamster anti-Mouse, FITC, Clone: HM79B, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB555303-Each-of-1 | In Stock | ₹ 32,707.50 |
BDB555303 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,707.50
GST (18%): ₹ 5,887.35
Total Price: ₹ 38,594.85
Antigen
CD79b
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Igβ
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
HM79B
Conjugate
FITC
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse B lymphoma, WEHI-123
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2
Related Products
Description
- The HM79b antibody reacts with an extracellular epitope of Ig β chain (Igβ or CD79b), a 35-40-kDa transmembrane protein which forms an 80-90-kDa disulfide-linked heterodimer with Ig α chain (Igα or CD79a, 30-35 kDa)
- On mature B lymphocytes, the CD79a/CD79b heterodimers are non-covalently associated with surface IgM to form the B-cell receptor complex (BCR)
- The presence of CD79a/CD79b is necessary for surface expression of the BCR and signal transduction via the BCR in B lymphocytes and pre-B cells
- It was recently reported that CD79b may be expressed on the cell surface preceding the appearance of surface IgM during B-lymphocyte development
- At this pro-B-cell stage, CD79b participates in signal transduction involved in the regulation of B-cell development
- It should be noted that multi-parameter flow cytometric analyses of bone marrow suspensions performed at BD Biosciences Pharmingen have been unable to detect surface staining by HM79b mAb on CD45R/B220+ IgM- cells.