BDB555666

CD86 Mouse anti-Human, PE-Cy5, Clone: IT2.2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB555666-Each-of-1 In Stock ₹ 32,574.00

BDB555666 - Each of 1

₹ 32,574.00

In Stock

Quantity

1

Base Price: ₹ 32,574.00

GST (18%): ₹ 5,863.32

Total Price: ₹ 38,437.32

Antigen

CD86

Classification

Monoclonal

Conjugate

PE-Cyanine5

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

IT2.2

Description

B70/B7-2

Host Species

Mouse

Quantity

100 Tests

Research Discipline

Immunology

Target Species

Human

Isotype

IgG2b κ

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Description

  • IT2.2 recognizes a 75kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells including lymphoid cells in germinal centers and Epstein-Barr virus transformed B-cell lines
  • CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in costimulation of T cells in primary immune response
  • Competitive binding assays demonstrate that, while both IT2.2 and FUN-1 (anti-CD86) recognize the same molecule, they react with different epitopes
  • IT2.2 blocks costimulation activity of CD86 in functional studies and blocks binding of human CTLA-4-Ig fusion protein to B70 gene-transfected cells
  • Host Species: Mouse Clone: IT2.2 Isotype: IgG2b, κ Species Reactivity: Human Flow Cytometry