BDB557003

P-glycoprotein Mouse anti-Human, PE, Clone: 17F9, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557003-Each-of-1 In Stock ₹ 38,270.00

BDB557003 - Each of 1

₹ 38,270.00

In Stock

Quantity

1

Base Price: ₹ 38,270.00

GST (18%): ₹ 6,888.60

Total Price: ₹ 45,158.60

Antigen

P-glycoprotein

Classification

Monoclonal

Conjugate

PE

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human MDR1 Transfected Cell Line

Quantity

100 Tests

Research Discipline

Cell Biology

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

17F9

Description

CD243; ABCB1; ABC20; CLCS; GP170; MDR1; P-GP; PGY1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • Reacts with a 170-180kDa transmembrane glycoprotein (P-glycoprotein), a product of the multidrug resistance-1 (MDR1) gene
  • This glycoprotein is expressed on MDR positive cells and has been reported to be expressed on many normal tissues, such as adrenal glands and endothelium, in the brain and skin
  • P-glycoprotein is known to impart drug resistance to cells by pumping many anti-cancer drugs out of the cytoplasm
  • 17F9 antibody binds to the surface of the viable, unfixed MDR+ cell line, PMG-Y (please inquire), and is able to partially block the binding of UIC2 antibody (another MDR-specific monoclonal antibody)
  • Immunoprecipitation application is reported, but not routinely tested in house
  • Host Species: Mouse Clone: 17F9 Isotype: IgG2b, κ Cross Reactivity: Human Flow Cytometry