BDB557437
CD18 Rat anti-Mouse, Unlabeled, Clone: M18/2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB557437-Each-of-1 | In Stock | ₹ 13,528.00 |
BDB557437 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,528.00
GST (18%): ₹ 2,435.04
Total Price: ₹ 15,963.04
Antigen
CD18
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Integrin β2 chain
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
M18/2
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse CTL glycoproteins
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
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Description
- Description The M18/2 antibody reacts with the common β 2 chain of LFA-1 (CD11a/CD18, α L β 2 integrin), Mac-1 (CD11b/CD18, α M β 2 integrin), and gp150, 95 (CD11c/CD18, α X β in vivo metastasis of the LB lymphoma to the spleen and that it blocks in vitro formation of aggregates of LB cells and splenocytes
- However, other reports indicate that mAb M18/2 has no effect on CTLmediated killing, adherence of C3bi-sensitized erythrocytes to Mac-1, antigen-specific binding of T cells to antigen-producing cells, or rejection of cardiac allografts
- Recent in vitro studies indicate that M18/2 antibody stimulates adhesion of Mac-1 to its ligands C3bi and ICAM-1, and it stimulates adhesion of LFA-1 to ICAM-1, but it has no effect upon the interactions of LFA-1 with ICAM-2 nor ICAM-3.