BDB557445
Ly-6G and Ly-6C Rat anti-Mouse, Unlabeled, Clone: RB6-8C5, BD
Manufacturer: Fischer Scientific
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Antigen
Ly-6G and Ly-6C
Classification
Monoclonal
Concentration
0.5mg/mL
Description
Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
RB6-8C5
Conjugate
Unconjugated
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Not Reported
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2b κ
Related Products
Description
- The RB6-8C5 antibody reacts with a common epitope on Ly-6G and Ly-6C, previously known as the myeloid differentiation antigen Gr-1
- In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation
- The antigen is also expressed on the monocyte lineage in the bone marrow, but not on erythroid cells
- In the periphery, RB6-8C5 antibody recognizes granulocytes (neutrophils and eosinophils) and monocytes
- The RB6-8C5 mAb is a component of the “lineage cocktail” used in studies of hematopoietic lineages
- The mAb 1A8 (Cat
- No
- 551461) specifically recognizes Ly-6G, but not Ly-6C
- This antibody is routinely tested by immunohistochemistry
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Rat Clone: RB6-8C5 Isotype: IgG2b κ Species Reactivity: Mouse Immunohistochemistry, Immunohistochemistry (Frozen)