BDB557498

Integrin b7 chain Rat anti-Mouse, PE, Clone: M293, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB557498-Each-of-1 In Stock ₹ 23,451.50

BDB557498 - Each of 1

₹ 23,451.50

In Stock

Quantity

1

Base Price: ₹ 23,451.50

GST (18%): ₹ 4,221.27

Total Price: ₹ 27,672.77

Antigen

Integrin b7 chain

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Integrin βp

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

M293

Conjugate

PE

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

αIELβ7 integrin from the C57BL/10 mouse T-cell hybridoma MTC-1

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG2a κ

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Description

  • Description The M293 antibody reacts with the integrin β7 chain (also known as integrin βp), which is found in association with either of two α chains
  • α4β7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells; it interacts with several ligands, including VCAM-1, fibronectin, and MAdCAM-1
  • αIELβ7 is found primarily on intestinal mucosal and intraepithelial lymphocytes (IEL), and it may be primarily involved in interactions between IEL and epithelia via recognition of E-cadherin
  • The epitope recognized by the mAb M293 has been mapped to the region between amino acids 387 and 542
  • The M293 antibody exhibits little or no activity in blocking β7 integrin-mediated adhesion
  • Host Species: Rat Clone: M293 Isotype: IgG2a, κ Species Reactivity: Mouse Immunogen: <special id='301'/>IEL<special id='302'/>7 integrin from the C57BL/10 mouse T-cell hybridoma MTC-1 Flow Cytometry