BDB558295
CD49b Hamster anti-Mouse, APC, Clone: HMA2, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558295-Each-of-1 | In Stock | ₹ 35,956.00 |
BDB558295 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,956.00
GST (18%): ₹ 6,472.08
Total Price: ₹ 42,428.08
Antigen
CD49b
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Integrin α2 chain
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
HMA2
Conjugate
APC
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse colon carcinoma cell line Colon26
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG1 κ
Related Products
Description
- The HMα2 antibody reacts with integrin α2 chain (CD49b), the 150-kDa transmembrane glycoprotein that non-covalently associates with the integrin β1 subunit (CD29) to form the integrin α2β1 complex known as VLA-2
- VLA-2, a receptor for collagen and laminin, is expressed on some splenic CD4+ T lymphocytes and NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, splenic NK cells, epithelial cells, and platelets; but it is not on thymocytes or Peyer’s-patch or lymphnode lymphocytes
- The expression of VLA-2 is upregulated on lymphocytes in response to mitogens
- The HMα2 antibody has been reported to partially block the interaction of T-cell blasts, but not NK cells, with collagen
- Purified HMα2 mAb blocks the staining of splenic NK cells by the anti-CD49b/Pan-NK Cells mAb DX5 (Cat
- No
- 553858, for the PE conjugate)
- Therefore, mAb HMα2 may be used like the DX5 mAb for identification of NK cells.