BDB557655
CD19 Rat anti-Mouse, APC-Cy7, Clone: 1D3, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB557655-Each-of-1 | In Stock | ₹ 22,428.00 |
BDB557655 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,428.00
GST (18%): ₹ 4,037.04
Total Price: ₹ 26,465.04
Antigen
CD19
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse CD19 Transfected Cell Line
Quantity
0.1 mg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
1D3
Conjugate
APC-Cyanine7
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 1D3 antibody reacts with CD19, a B lymphocyte-lineage differentiation antigen
- CD19, a 95-kDa transmembrance glycoprotein, is a member of the immunoglobulin superfamily and is expressed throughout B-lymphocyte development from the pro-B cell throughthe mature B-cell stages
- Terminally differentiated plasma cells do not express CD19
- On the surface of mature B cells, the CD19 molecule associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to promote cellular activation
- Studies with CD19-deficient mice have suggested that the level of CD19 expression affects the generation and maturation of B cells in the bone marrow and periphery
- B-1 lineage B cells, also known as CD5+ B cells, are drastically reduced or absent in CD19-deficient mice
- Increased levels of CD19 expression correlate with increased frequencies of peritonal and splenic B-1 cells and reduced numbers of conventional B lymphocytes in the periphery
- CD19 participates in B-lymphocyte development, B-cell activation, maturation of memory B cells and regulation of tolerance
- CD19 has also been detected on peritoneal mast cells, co-localized with CD21/CD35, and it is proposed to play a role in complement-mediated mast-cell activation.