BDB557847
NKp46 Mouse anti-Human, Unlabeled, Clone: 9E2/NKP46, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB557847-Each-of-1 | In Stock | ₹ 49,840.00 |
BDB557847 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,840.00
GST (18%): ₹ 8,971.20
Total Price: ₹ 58,811.20
Antigen
NKp46
Classification
Monoclonal
Concentration
1.0mg/mL
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
Human NKp46 Recombinant Protein
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
9E2/NKP46
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
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Description
- NKp46, a major cytoxicity receptor of NK cells, is a type I membrane glycoprotein (46kDaa) is expressed on resting and activated NK cells
- Its extracellular region contains two C2-type, Ig-like domains
- The transmembrane domain contains a positively charged amino acid (Arg) which could be involved in stabilizing the association with CD3ζ
- Its intracellular region does not contain immunoreceptor tyrosine-based activating motifs (ITAM), but it is linked to intracytoplasmic transduction machinery by its association with CD3ζ and FcεRIγ adaptor proteins
- NKp46 along with NKp30 and NKp44 are referred to as natural cytoxicity receptors (NCR) and play a very important role in killing virus-infected, tumor cells and MHC-class I-unprotected cells
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: 9E2 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry