BDB559502

IL-17A Rat anti-Mouse, PE, Clone: TC11-18H10, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB559502-Each-of-1 In Stock ₹ 26,299.50

BDB559502 - Each of 1

₹ 26,299.50

In Stock

Quantity

1

Base Price: ₹ 26,299.50

GST (18%): ₹ 4,733.91

Total Price: ₹ 31,033.41

Antigen

IL-17A

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Recombinant Mouse IL-17 Protein

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Mouse

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

TC11-18H10

Conjugate

PE

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The TC11-18H10 monoclonal antibody specifically binds to recombinant and natural mouse IL-17A proteins
  • IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses
  • Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells
  • It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo
  • The TC11-18H10 antibody has been reported to neutralize IL-17A activity
  • Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways
  • The mouse IL-17A cDNA was isolated from a cDNA library generated from TCR αβ +CD4-CD8- thymocytes.