BDB559780

CD141 Mouse anti-Human, Unlabeled, Clone: 1A4, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB559780-Each-of-1 In Stock ₹ 14,658.30

BDB559780 - Each of 1

₹ 14,658.30

In Stock

Quantity

1

Base Price: ₹ 14,658.30

GST (18%): ₹ 2,638.494

Total Price: ₹ 17,296.794

Antigen

CD141

Classification

Monoclonal

Concentration

0.5mg/mL

Description

Thrombomodulin; TM; THBD; THRM; AHUS6; Fetomodulin; BDCA-3

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C

Applications

Flow Cytometry

Clone

1A4

Conjugate

Unconjugated

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

Purified Human Thrombomodulin

Quantity

0.1 mg

Research Discipline

Immunology

Target Species

Human

Isotype

IgG1 κ

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Description

  • The 1A4 monoclonal antibody specifically binds to a 75 kDa, a single chain, type I membrane glycoprotein referred to as thrombomodulin and fetomodulin
  • CD141 is expressed on endothelial cells, smooth muscle cells, epithelial cells, synovial lining cells, and keratinocytes
  • It is also found on megakaryocytes, dendritic cells, peripheral blood moncytes, and neutrophils, but not on lymphocytes
  • Reports indicate that CD141 plays an important role in Protein C activation and the initiation of the Protein C anticoagulant pathway
  • Thrombin loses its procagulant function when it binds to CD141, and the CD141/thrombin complex is able to activate Protein C.