BDB559786
CD226 Mouse anti-Human, NA/LE, Unlabeled, Clone: DX11, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB559786-Each-of-1 | In Stock | ₹ 53,266.50 |
BDB559786 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,266.50
GST (18%): ₹ 9,587.97
Total Price: ₹ 62,854.47
Antigen
CD226
Classification
Monoclonal
Concentration
1.0mg/mL
Description
DNAM-1; DNAM1; PTA1; PTA-1; TLiSA1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C
Applications
Flow Cytometry
Clone
DX11
Conjugate
Unconjugated
Formulation
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
Human CTL Clone
Quantity
0.5 mg
Research Discipline
Immunology
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Reacts with DNAX accessory molecule-1 (DNAM-1), a 65kDa transmembrane glycoprotein consisting of 318 amino acid residues including two Ig-like domains
- DNAM-1 is expressed on the majority of T cells, NK cells, monocytes, and a subset of B cells, but not on granulocytes or erythrocytes
- It is also present on a subset of thymocytes coexpressing high density surface CD3
- DNAM-1 is not present on normal fibroblast cell lines or tumor cell lines of epithelial or neuronal origins
- DNAM-1 is a tyrosinephosphorylated, signal-transducing molecule which participates in primary adhesion during cytotoxic T lymphocyte (CTL)-mediated cytotoxicity
- DX11 inhibits T- and NKcell-mediated cytotoxicity against a variety of tumor cell targets, and blocks cytokine production by alloantigen-specific T cells
- Flow Cytometry