BDB560402
Foxp3 Rat anti-Mouse, Alexa Fluor 647, Clone: MF23, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB560402-Each-of-1 | In Stock | ₹ 24,208.00 |
BDB560402 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,208.00
GST (18%): ₹ 4,357.44
Total Price: ₹ 28,565.44
Antigen
Foxp3
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Forkhead box p3; Forkhead box protein p3; JM2; Scurfin; Scurfy; Sf
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
MF23
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen
Mouse Foxp3 Recombinant Protein
Quantity
25 μg
Research Discipline
Immunology
Target Species
Mouse
Isotype
IgG2b
Related Products
Description
- Foxp3 is a 50-55kDa protein also known as Forkhead box P3, JM2, or IPEX
- It is a member of the forkhead or winged helix family of transcription factors and is specifically expressed by T regulatory (Treg) cells
- Foxp3 has been reported to be a key regulatory protein for Treg cell development and function
- Ectopic expression of Foxp3 in conventional T cells is sufficient to induce suppressive activity, repress the production of cytokines such as IL2 and IFN-γ, and upregulate Treg cell-associated molecules such as CD25, CTLA4 and GITR
- It has been found that the mutation of Foxp3 is responsible for “scurfy” mice
- When overexpressed, Foxp3 leads to poor T cell proliferation and activation
- Monoclonal antibody MF23 reacts with mouse Foxp3
- Immunoblotting with MF23 antibody has confirmed it recognizes an epitope between 1-87 amino acids in the N-terminal domain
- Host Species: Rat Clone: MF23 Isotype: IgG2b Species Reactivity: Mouse Immunogen: Mouse Foxp3 Recombinant Protein Intracellular Staining