BDB561146
CD23 Mouse anti-Human, FITC, Clone: M-L233, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561146-Each-of-1 | In Stock | ₹ 20,470.00 |
BDB561146 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,470.00
GST (18%): ₹ 3,684.60
Total Price: ₹ 24,154.60
Antigen
CD23
Classification
Monoclonal
Conjugate
FITC
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
M-L233
Description
FCER2; FcεRII; Low affinity immunoglobulin epsilon Fc receptor; BLAST-2
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- The M-L233 antibody specifically binds to human CD23, the low affinity receptor for human IgE (FcεRII)
- CD23 is a type II membrane glycoprotein that can be expressed by B cells, monocytes, macrophages, eosinophils, platelets and dendritic cells
- CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils
- Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23
- Larger fragments of sCD23 (e.g., 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not
- Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.