BDB561180
CD338 Mouse anti-Human, PE, Clone: 5D3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561180-Each-of-1 | In Stock | ₹ 32,574.00 |
BDB561180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,574.00
GST (18%): ₹ 5,863.32
Total Price: ₹ 38,437.32
Antigen
CD338
Classification
Monoclonal
Conjugate
PE
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human ABCG2-transfected Mouse cells
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
5D3
Description
ABCG2; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CDw338; EST157481; MGC102821
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2b κ
Related Products
Description
- The 5D3 monoclonal antibody specifically binds to an epitope of ABCG2 (BCRP1), a multi-drug resistance protein that is a member of ATP binding cassette (ABC) transporters
- It is highly expressed on primitive stem cells as identified by the “side-population” (SP) phenotype
- This SP phenotype is based on the efflux of fluorescent dyes such as Rhodamine 123 and Hoechst 33342
- The expression of ABCG2 appears to be highly conserved as it has been identified in various species
- Studies show that highly purified murine stem cells express BCRP1 mRNA and this expression declines sharply as the stem cells express CD34
- The highest levels of BCRP1 mRNA expression have been seen in KDR+ human stem cells
- ABCG2/BCRP1 was clustered as CD338 in the HLDA8 workshop.