BDB561694
CD123 Mouse anti-Human, FITC, Clone: 7G3, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561694-Each-of-1 | In Stock | ₹ 9,300.50 |
BDB561694 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,300.50
GST (18%): ₹ 1,674.09
Total Price: ₹ 10,974.59
Antigen
CD123
Classification
Monoclonal
Conjugate
FITC
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human IL-3Ra-transfected cells
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
7G3
Description
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Related Products
Description
- Reacts with human CD123, the 70kDa IL-3 receptor α chain (IL-3Rα), which associates with the 120-140kDa β subunit
- The β chain is shared with the receptors for interleukins IL-5 and GM-CSF
- IL-3Rα is expressed on hematopoietic progenitors and plays an important role in hematopoietic progenitor cell growth and differentiation
- This antibody has been reported to block the binding of 125I-IL-3 to high and low affinity IL-3 receptors
- In functional experiments, this antibody was found to inhibit acute myeloid leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration
- This antibody has been reported to be useful for immunoprecipitation, western blot and immunofluorescent staining for flow cytometry
- At the Fifth HLDA Workshop, the human IL-3 receptor was designated CD123.