BDB561939
CD71 Mouse anti-Human, FITC, Clone: M-A712, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB561939-Each-of-1 | In Stock | ₹ 11,748.00 |
BDB561939 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,748.00
GST (18%): ₹ 2,114.64
Total Price: ₹ 13,862.64
Antigen
CD71
Classification
Monoclonal
Conjugate
FITC
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Immunogen
T-CLL and Jurkat Cells
Quantity
25 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
M-A712
Description
TFR; TFRC; Trfr; TfR1; Transferrin receptor protein 1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG2a κ
Related Products
Description
- The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR)
- This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers
- CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells
- CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens
- Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin
- After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface.