BDB562230

CD146, Alex-fluor 647 Rat anti-Mouse, Alexa Fluor 647, Clone: ME-9F1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562230-Each-of-1 In Stock ₹ 21,538.00

BDB562230 - Each of 1

₹ 21,538.00

In Stock

Quantity

1

Base Price: ₹ 21,538.00

GST (18%): ₹ 3,876.84

Total Price: ₹ 25,414.84

Antigen

CD146

Classification

Monoclonal

Concentration

0.2mg/mL

Description

S-endo 1; S-endo; Muc18; Mcam; Gicerin

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

ME-9F1

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

CBa/J Mouse lymph node Cell Line

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The ME-9F1 monoclonal antibody specifically binds to mouse CD146
  • The CD146 adhesion molecule is a type 1 transmembrane glycoprotein and member of the immunoglobulin superfamily
  • CD146 is expressed by blood vessel endothelial cells and may play roles in forming intercellular junctions between endothelial cells and influencing the transendothelial migration of other cell types
  • CD146 is also expressed by some melanoma cell lines, NK cells and neutrophils
  • CD146 is not detectable on mouse monocytes, dendritic cells, T cells, NKT cells, B cells and smooth muscle cells
  • Increased expression of CD146 is reportedly associated with NK cell maturation and may be used to characterize different functional NK cell subsets
  • Activated CD146-positive mouse NK cells reportedly are less cytotoxic and secrete less IFN-γ than their CD146-negative counterparts.