BDB564394

CD49d Rat anti-Mouse, Alexa Fluor 647, Clone: R1-2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB564394-Each-of-1 In Stock ₹ 23,095.50

BDB564394 - Each of 1

₹ 23,095.50

In Stock

Quantity

1

Base Price: ₹ 23,095.50

GST (18%): ₹ 4,157.19

Total Price: ₹ 27,252.69

Antigen

CD49d

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Integrin α4 chain

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

R1-2

Conjugate

Alexa Fluor 647

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

AKR/Cum mouse spontaneous T lymphoma line TK1

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The R1-2 antibody reacts with the integrin α 4 chain (CD49d), which is expressed as a heterdimer with either of two β , β 1 or β 7 (also known as β p)
  • The α 4β α 4β 7 also preferentially binds to the mucosal vascular addressin, MAdCAM-1
  • The R1-2 antibody blocks some α 4 integrin-mediated binding functions
  • In combination with mAb 9C10 (MFR4.B) (Cat
  • No
  • 553313), binding of VLA-4 expressing cells to VCAM-1 can be almost completely inhibited.