BDB562632
CD11b/MAC-1 Mouse anti-Human, Brilliant Violet 421, Clone: ICRF44 (also known as 44), BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562632-Each-of-1 | In Stock | ₹ 38,092.00 |
BDB562632 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,092.00
GST (18%): ₹ 6,856.56
Total Price: ₹ 44,948.56
Antigen
CD11b
Classification
Monoclonal
Conjugate
Brilliant Violet 421
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human monocytes
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
ICRF44 (also known as 44)
Description
Mac-1α, integrin αM subunit, CR3 α chain
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3
- CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells
- CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3)
- This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP
- The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
- With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
- BD Horizon™ BV421conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.