BDB562940
CD66B Mouse anti-Human, Brilliant Violet 421, Clone: G10F5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562940-Each-of-1 | In Stock | ₹ 40,584.00 |
BDB562940 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,584.00
GST (18%): ₹ 7,305.12
Total Price: ₹ 47,889.12
Antigen
CD66B
Classification
Monoclonal
Conjugate
Brilliant Violet 421
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human Granulocytes
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
G10F5
Description
CEACAM8; CGM6; NCA-95
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgM κ
Related Products
Description
- The G10F5 monoclonal antibody specifically binds to CD66b, also known as Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8)
- CD66b is a glycosylphosphatidylinositol (GPI) linked protein with amolecular weight of 100 kDa expressed on granulocytes
- This molecule was previously clustered as CD67 in the Fourth Human Leucocyte DifferentiationAntigen (HLDA) Workshop and renamed CD66b in the Fifth HLDA Workshop
- CD66b is a member of the carcinoembryonic antigen (CEA)-like glycoprotein family present on granulocytes and referred to as non-specific crossreacting antigens (NCA)
- Granulocyte activation induced with soluble stimulators (calcium ionophore, phorbol myristate acetate, N-formylmethionyl- leucyl-phenylalanine) results in release and increased expression of NCA
- Findings suggest that these molecules may play a role in phagocytosis, chemotaxis and adherence
- The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
- With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
- BD Horizon™ BV421conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.