BDB562817

CD73 Mouse anti-Human, PE-CF594, Clone: AD2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562817-Each-of-1 In Stock ₹ 37,558.00

BDB562817 - Each of 1

₹ 37,558.00

In Stock

Quantity

1

Base Price: ₹ 37,558.00

GST (18%): ₹ 6,760.44

Total Price: ₹ 44,318.44

Antigen

CD73

Classification

Monoclonal

Conjugate

PE-CF594

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Pre-B leukemia cell line

Quantity

100 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

AD2

Description

NT5E; 5' nucleotidase; 5'-NT; E5NT; Ecto-5'-nucleotidase; eN; eNT; NT; NT5

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The AD2 monoclonal antibody specifically binds to ecto-5’-nucleotidase, a 70 kDa, glycosyl phosphatidylinositol (GPI)-anchored glycoprotein
  • CD73 is expressed on subsets of T and B lymphocytes, follicular dendritic cells, epithelial cells, endothelial cells and mesenchymal stem cells
  • Its expression on lymphocytes increases during T and B cell development
  • CD73 has enzymatic activity and catalyzes the dephosphorylation of adenosine monophosphate (AMP) converting it to adenosine
  • It has been suggested that CD73 can mediate costimulatory signals in T cell activation and adhesion of lymphocytes to endothelium
  • This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™
  • PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics
  • Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).