BDB562854

CD33 Mouse anti-Human, Brilliant Violet 421, Clone: WM53, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB562854-Each-of-1 In Stock ₹ 27,367.50

BDB562854 - Each of 1

₹ 27,367.50

In Stock

Quantity

1

Base Price: ₹ 27,367.50

GST (18%): ₹ 4,926.15

Total Price: ₹ 32,293.65

Antigen

CD33

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Acute Myeloid Leukemia Blasts

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

WM53

Description

Siglec-3; SIGLEC3; Sialic acid-binding Ig-like lectin 3; p67; gp67; My9

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The WM53 monoclonal antibody specifically binds to human CD33
  • CD33 is a 67 kDa type I transmembrane glycoprotein
  • It is expressed on monocytes, activated T cells, myeloid progenitors, mast cells and weakly on polymorphonuclear cells
  • CD33 is absent on normal platelets, lymphocytes, erythrocytes, and hematopoietic stem cells
  • Reports indicate that this glycoprotein can function as a sialic acid-dependent cell adhesion molecule and this function can be modulated by endogenous sialoglycoconjugates when CD33 is expressed on the membrane
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.