BDB562897
KLRG1 Hamster anti-Mouse, Brilliant Violet 421, Clone: 2F1, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB562897-Each-of-1 | In Stock | ₹ 27,234.00 |
BDB562897 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,234.00
GST (18%): ₹ 4,902.12
Total Price: ₹ 32,136.12
Antigen
KLRG1
Classification
Monoclonal
Concentration
0.2mg/mL
Description
Klrg1; Killer cell lectin-like receptor subfamily G member 1; MAFA
Host Species
Hamster
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Mouse
Isotype
IgG2 κ
Applications
Flow Cytometry
Clone
2F1
Conjugate
Brilliant Violet 421
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
A-LAK from C57BL/6 mice
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Related Products
Description
- The 2F1 monoclonal antibody specifically binds to KLRG1 ( K iller cell L ectin-like R eceptor mmunoreceptor T yrosine-based I nhibitory M otif);its ligand has not beenidentified KLRG1 is expressed mainly as a homodimeric molecule consisting of two N-glycosylated subunits of approximately 30-38 kDa
- The level of KLRG1 expression is reduced in MHC class I-deficient mice, although direct binding of KLRG1 to MHC class I antigens could not be detected
- Cross-linking of KLRG1 by 2F1 mAb reduces TCR-mediated Ca++mobilization and cytotoxic responses (but not IFN-γ production) by CD8+ T cellsand inhibits IFN-γ and TNF-αproduction and redirected lysis by NK cells.