BDB563595

KLRG1 Rat anti-Mouse, PerCP-Cy5.5, Clone: 2F1, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563595-Each-of-1 In Stock ₹ 19,046.00

BDB563595 - Each of 1

₹ 19,046.00

In Stock

Quantity

1

Base Price: ₹ 19,046.00

GST (18%): ₹ 3,428.28

Total Price: ₹ 22,474.28

Antigen

KLRG1

Classification

Monoclonal

Concentration

0.2mg/mL

Description

Klrg1; Killer cell lectin-like receptor subfamily G member 1; MAFA

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Mouse

Isotype

IgG2 κ

Applications

Flow Cytometry

Clone

2F1

Conjugate

PerCP-Cyanine5.5

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen

A-LAK from C57BL/6 mice

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

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Description

  • The 2F1 monoclonal antibody specifically binds to KLRG1 ( K iller cell L ectin-like R eceptor mmunoreceptor T yrosine-based I nhibitory M otif);its ligand has not beenidentified KLRG1 is expressed mainly as a homodimeric molecule consisting of two N-glycosylated subunits of approximately 30-38 kDa
  • The level of KLRG1 expression is reduced in MHC class I-deficient mice, although direct binding of KLRG1 to MHC class I antigens could not be detected
  • Cross-linking of KLRG1 by 2F1 mAb reduces TCR-mediated Ca++mobilization and cytotoxic responses (but not IFN-γ production) by CD8+ T cellsand inhibits IFN-γ and TNF-αproduction and redirected lysis by NK cells.