BDB564679
CD66b Mouse anti-Human, BB515, Clone: G10F5, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB564679-Each-of-1 | In Stock | ₹ 26,299.50 |
BDB564679 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,299.50
GST (18%): ₹ 4,733.91
Total Price: ₹ 31,033.41
Antigen
CD66b
Classification
Monoclonal
Conjugate
Brilliant Blue 515 (BB515)
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide
Immunogen
Human Granulocytes
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
G10F5
Description
CEACAM8; CGM6; NCA-95
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgM κ
Related Products
Description
- The G10F5 monoclonal antibody specifically binds to CD66b, also known as Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8)
- CD66b is a glycosylphosphatidylinositol (GPI) linked protein with a molecular weight of 100 kDa expressed on granulocytes
- This molecule was previously clustered as CD67 in the Fourth Human Leucocyte Differentiation Antigen (HLDA) Workshop and renamed CD66b in the Fifth HLDA Workshop
- CD66b is a member of the carcinoembryonic antigen (CEA)-like glycoprotein family present on granulocytes and referred to as non-specific crossreacting antigens (NCA)
- Granulocyte activation induced with soluble stimulators (calcium ionophore, phorbol myristate acetate, N-formylmethionyl- leucyl-phenylalanine) results in release and increased expression of NCA
- Findings suggest that these molecules may play a role in phagocytosis, chemotaxis and adherence
- The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences
- With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter)
- This dye provides a much brighter alternative to FITC with less spillover into the PE detector.