BDB563156
CD183 Mouse anti-Human, Brilliant Violet 711, Clone: 1C6/CXCR3, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563156-Each-of-1 | In Stock | ₹ 28,124.00 |
BDB563156 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,124.00
GST (18%): ₹ 5,062.32
Total Price: ₹ 33,186.32
Antigen
CD183
Classification
Monoclonal
Conjugate
Brilliant Violet 711
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human CXCR3 Peptide
Quantity
50 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
1C6/CXCR3
Description
CXCR3; C-X-C chemokine receptor type 3; GPR9; IP10R; MigR; CKRL2; CMKAR3
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype
IgG1 κ
Related Products
Description
- The 1C6/CXCR3 monoclonal antibody specifically binds to human CD183, also known as the CXCR3 chemokine receptor
- CD183 is a 40-41 kDa seven-transmembrane protein and member of the G protein-coupled receptor family
- CD183 is expressed primarily on activated T cells that infiltrate inflammatory sites
- It has also been detected on some circulating T cells, B cells, and NK cells
- Reports show that some CXCR3-positive T cells also express CCR5 and are mostly CD45RO-positive cells
- Three ligands for CXCR3 have been identified
- They are CXCL9 (Mig/monokine induced by interferon-γ), CXCL10 (IP-10/interferon-γinducible 10-kD protein), and CXCL11 (I-TAC/interferon-inducible T-cell alpha chemoattractant)
- These chemokines are produced by a variety of cells upon stimulation by IFN-γand interact with CXCR3 to mediate T-cell chemotaxis
- This reagent has been reported to be suitable for immunohistochemical staining of acetone-fixed, frozen sections and/or formalin-fixed, paraffin-embedded tissue sections with citrate pretreatment
- Clone 1C6/CXCR3 also cross reacts with a subset of peripheral blood lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys
- The distribution of lymphocytes is similar to that observed with CD183-positive peripheral blood lymphocytes from normal human donors
- CXCR3 has been clustered as CD183 in the VIIth HLDA workshop.