BDB563346

CD20 Mouse anti-Human, Brilliant Violet 421, Clone: H1 (also known as FB1), BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB563346-Each-of-1 In Stock ₹ 29,681.50

BDB563346 - Each of 1

₹ 29,681.50

In Stock

Quantity

1

Base Price: ₹ 29,681.50

GST (18%): ₹ 5,342.67

Total Price: ₹ 35,024.17

Antigen

CD20

Classification

Monoclonal

Conjugate

Brilliant Violet 421

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Human B lymphoma cell line

Quantity

50 Tests

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

H1 (also known as FB1)

Description

MS4A1; membrane-spanning 4-domains subfamily A member 1; B1; Bp35; LEU-16

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

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Description

  • The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20
  • CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation
  • Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported
  • The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival
  • The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences
  • The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes
  • With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter)
  • BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.