BDB563494
CD135 Mouse anti-Human, Alexa Fluor 647, Clone: 4G8, BD
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB563494-Each-of-1 | In Stock | ₹ 28,658.00 |
BDB563494 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 28,658.00
GST (18%): ₹ 5,158.44
Total Price: ₹ 33,816.44
Antigen
CD135
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Human FLT3 Transfected Cell Line
Quantity
100 Tests
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
4G8
Description
FLK2; FLT-3; Fms-related tyrosine kinase 3; STK-1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 4G8 monoclonal antibody specifically binds to CD135 which is also known as FMS-like tyrosine kinase 3 (FLT3), Fetal liver kinase 2 (FLK2) and Stem cell tyrosine kinase 1 (STK1)
- CD135 is a 155-160 kDa type I transmembrane glycoprotein
- It belongs to subclass III of the receptor tyrosine kinase (RTK) family which includes receptors for M-CSF (CD115), SCF/c-Kit Ligand (CD117), and PDGF (CD140a and CD140b)
- CD135 is expressed on multipotential, myelomonocytic and primitive B-cell progenitors
- The most primitive hematopoietic progenitor cells express low levels of CD135
- CD135 plays the role of growth factor receptor for early hematopoietic progenitors
- Reports from studies with knockout mice have shown that targeted CD135 disruption impaired the development of primitive progenitor cells of all hematopoietic lineages with significant impact on lymphopoietic precursors.